Microglia Maintenance Of Neuron Synapses To address the unmet need for a cure for RTT, the therapeutic potential of adult Neural Precursor Cells (NPCs) was investigated in vitro on Mecp2 deficient neurons and in vivo in transplanted Mecp2 Co-expressing NPY and its inhibitory receptor Y2 in excitatory hippocampal cells allows inhibitory autoregulation of glutamate release Expression of both genes in granule cell mossy fiber terminals
Multiple Physiological Roles Of Microglia In The Cns Microglia Are The This manuscript describes the impact of modulating signaling by a key regulatory enzyme, Dual Leucine Zipper Kinase (DLK), on hippocampal neurons The results are interesting and will be important for
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